Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 2/20 | 0.31 |
| ▸ | CPA1 | P15085 | 2/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230433 | 1.00 | ALDH1A1 (0.31) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL14614609 | 1.00 | ALDH1A1 (0.31) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL19230447 | 1.00 | ALDH1A1 (0.31) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL19545995 | 1.00 | ALDH1A1 (0.31) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL3527314 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL196730 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL3149648 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL196729 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL14889910 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL19729258 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786185-A1 | HUMANIZED ANTIBODIES TO LIV-1 AND USE OF SAME TO TREAT CANCER | Seagen Inc. (US) | 2021-03-03 | — | — | EP | disclosed |