Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889910 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL3527314 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL196729 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL3149648 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL17772985 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL3154732 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL8708558 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL3156914 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL28389417 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL3154725 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240036055-A1 | Multiplexed DiLeu-Biotin-Azide (DBA) Tag Enabled Isobaric Tandem Orthogonal Proteolysis Activity-Based Protein Profiling (isoBOP-ABPP) Platform For High-Throughput Quantitative Pan-PTM Analysis | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2024-02-01 | — | — | US | claimed |
| US-20160244484-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2016-08-25 | — | — | US | claimed |
| EP-3049428-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2016-08-03 | — | — | EP | claimed |
| WO-2015040235-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-03-26 | — | — | WO | claimed |
| EP-2477962-A1 | PRODRUGS OF GUANFACINE | Shire LLC (US) | 2012-07-25 | — | — | EP | claimed |
| US-20120178666-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2012-07-12 | — | — | US | claimed |
| WO-2011033296-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2011-03-24 | — | — | WO | claimed |
| US-20110065796-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2011-03-17 | — | — | US | claimed |
| EP-0842142-B1 | PROCESS FOR PRODUCING ALPHA-(N,N DIALKYL)-AMINO CARBOXYLIC ACID AMIDES | BASF AG (DE) | 2001-09-26 | — | — | EP | claimed |
| US-5945543-A | REACTING CORRESPONDING FREE ACIDS WITH PRIMARY OR SECONDARY AMINES IN THE PRESENCE OF ANHYDRIDES OF AN ALKANEPHOSPHONIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | claimed |
| EP-0842142-A1 | PROCESS FOR PRODUCING $g(a)-(N,N DIALKYL)-AMINO CARBOXYLIC ACID AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-20 | — | — | EP | claimed |
| WO-1997005096-A1 | PROCESS FOR PRODUCING α-(N,N DIALKYL)-AMINO CARBOXYLIC ACID AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-13 | — | — | WO | claimed |
| US-12427472-B2 | Process for removal of acid gases from a fluid stream | BASF SE (DE) | 2025-09-30 | — | — | US | disclosed |
| CN-114173908-B | Method for removing acid gases from fluid streams | 巴斯夫欧洲公司 | 2025-04-01 | — | — | CN | disclosed |
| US-12138583-B2 | Process for removal of acid gases from a fluid stream with a liquid absorbent comprising a piperazine ring | BASF SE (DE) | 2024-11-12 | — | — | US | disclosed |
| US-20240042375-A1 | PROCESS FOR REMOVAL OF ACID GASES FROM A FLUID STREAM | BASF SE (DE) | 2024-02-08 | — | — | US | disclosed |
| WO-1996040751-A1 | NOVEL DOLASTATIN DERIVATIVES, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040752-A1 | NOVEL DOLASTATIN DERIVATIVES, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1996-12-19 | — | — | WO | disclosed |
| EP-0674652-A1 | DOLOSTATIN ANALOG | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994013695-A1 | DOLOSTATIN ANALOG | BASF AKTIENGESELLSCHAFT (DE) | 1994-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12427472-B2 | Process for removal of acid gases from a fluid stream | C5, C1S, C9 | ALDH1A1 469/4885MME 942/4885ACE 1998/4885 |
| US-20160244484-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | VIP, TNF, ENPEP | ALDH1A1 2456/4885MME 202/4885ACE 535/4885 |
| US-20240042375-A1 | PROCESS FOR REMOVAL OF ACID GASES FROM A FLUID STREAM | C5, C1S, C9 | ALDH1A1 469/4885MME 942/4885ACE 1998/4885 |
| US-20120178666-A1 | PRODRUGS OF GUANFACINE | DNPEP, VIP, GDA | ALDH1A1 677/4885MME 62/4885ACE 49/4885 |
| US-12138583-B2 | Process for removal of acid gases from a fluid stream with a liquid absorbent comprising a piperazine ring | AVPR2, HRH2, SLC43A1 | ALDH1A1 275/4885MME 3622/4885ACE 4290/4885 |
| US-20110065796-A1 | PRODRUGS OF GUANFACINE | DNPEP, VIP, GDA | ALDH1A1 677/4885MME 62/4885ACE 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.