Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23049698 | 0.71 | PHGDH (0.58) | PHGDH | |
| SCHEMBL28483927 | 0.71 | RORC (0.43) | — | |
| SCHEMBL23049726 | 0.70 | PHGDH (0.51) | PHGDH | |
| SCHEMBL23049657 | 0.68 | PHGDH (0.52) | PHGDH | |
| SCHEMBL35211852 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL23049702 | 0.66 | PHGDH (0.50) | PHGDH | |
| SCHEMBL24186313 | 0.65 | PHGDH (0.41) | PHGDH | |
| SCHEMBL2909623 | 0.63 | CYP19A1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL13684845 | 0.63 | MAPT (0.39) | — | |
| SCHEMBL23049713 | 0.63 | PHGDH (0.43) | PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596064-B1 | TOSYLACETATE BASED COMPOUNDS AND DERIVATIVES THEREOF AS PHGDH INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-03-03 | — | — | EP | disclosed |