Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL81419 | 1.00 | CA4 (0.42) | — | |
| Bicarbonate SCHEMBL2050659 | 1.00 | CA4 (0.42) | — | |
| Bicarbonate SCHEMBL410564 | 0.95 | CA4 (0.39) | — | |
| Bicarbonate SCHEMBL6536657 | 0.95 | CA4 (0.39) | — | |
| Bicarbonate SCHEMBL1115493 | 0.95 | CA4 (0.39) | — | |
| Bicarbonate SCHEMBL904478 | 0.95 | CA4 (0.39) | — | |
| Bicarbonate SCHEMBL1003571 | 0.95 | CA4 (0.39) | — | |
| Bicarbonate SCHEMBL2301863 | 0.95 | CA4 (0.39) | — | |
| Bicarbonate SCHEMBL950160 | 0.94 | — | — | |
| Bicarbonate SCHEMBL13725826 | 0.94 | CA4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116165-A9 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | NEXT SAFETY INC (US) | 2009-06-11 | — | — | WO | claimed |
| WO-2008116165-A2 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | NEXT SAFETY, INC. (US) | 2008-09-25 | — | — | WO | claimed |
| US-20080066741-A1 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | HUNTER, CHARLES ERIC | 2008-03-20 | — | — | US | claimed |
| EP-4255541-A1 | PRODUCT DELIVERY DEVICES AND METHODS | Breathe Restore, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022118225-A1 | PRODUCT DELIVERY DEVICES AND METHODS | BREATHE RESTORE, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| US-9554989-B2 | Silk reservoirs for drug delivery | TRUSTEES OF TUFTS COLLEGE (US) | 2017-01-31 | — | — | US | disclosed |
| EP-2349493-B1 | ANTIPERSPIRANT PREPARATIONS COMPRISING HYDROTALCITE | BEIERSDORF AG (DE) | 2016-07-06 | — | — | EP | disclosed |
| US-20150045764-A1 | SILK RESERVOIRS FOR DRUG DELIVERY | TRUSTEES OF TUFTS COLLEGE | 2015-02-12 | — | — | US | disclosed |
| EP-2827884-A1 | SILK RESERVOIRS FOR DRUG DELIVERY | Trustees Of Tufts College (US) | 2015-01-28 | — | — | EP | disclosed |
| WO-2013142119-A1 | SILK RESERVOIRS FOR DRUG DELIVERY | TRUSTEES OF TUFTS COLLEGE (US) | 2013-09-26 | — | — | WO | disclosed |
| EP-2349494-A2 | ANTIPERSPIRANT STICK | Beiersdorf AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| EP-2349493-A2 | ANTIPERSPIRANT PREPARATIONS COMPRISING HYDROTALCITE | Beiersdorf AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010046010-A2 | ANTIPERSPIRANT PREPARATIONS COMPRISING HYDROTALCITE | BEIERSDORF AG (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046012-A2 | WATER-FREE ANTIPERSPIRANT STICKS COMPRISING MICROCRYSTALLINE WAX | BEIERSDORF AG (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046011-A2 | ANTIPERSPIRANT STICK WITHOUT VOLATILE CARRIER OILS | BEIERSDORF AG (DE) | 2010-04-29 | — | — | WO | disclosed |
| US-5382384-A | Thermoplastic and thermosetting blends for heat resistance | RAYCHEM CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |