Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2304976 | 1.00 | — | — | |
| Bicarbonate SCHEMBL2050659 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL410564 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6536657 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1115493 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL904478 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1003571 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2301863 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL950160 | 0.94 | — | — | |
| Bicarbonate SCHEMBL13725826 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114381057-B | Polyethylene resin composition for beverage caps and products produced from the composition | 韩华道达尔能源有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-114904457-A | Continuous production equipment and process for carbonate type layered magnesium aluminum hydroxide neutralized by mother liquor carbon | 自然资源部天津海水淡化与综合利用研究所 | 2022-08-16 | — | — | CN | claimed |
| CN-114381057-A | Polyethylene resin composition for beverage cap and product produced from the same | 韩华道达尔有限公司 | 2022-04-22 | — | — | CN | claimed |
| US-11198798-B2 | Self-fusing silicone tape compositions having corrosion inhibitors therein | NORTHERN TECHNOLOGIES INTERNATIONAL CORPORATION (US) | 2021-12-14 | — | — | US | claimed |
| US-20200277516-A1 | SELF-FUSING SILICONE TAPE COMPOSITIONS HAVING CORROSION INHIBITORS THEREIN | NORTHERN TECHNOLOGIES INTERNATIONAL CORPORATION | 2020-09-03 | — | — | US | claimed |
| WO-2019070927-A1 | SELF-FUSING SILICONE TAPE COMPOSITIONS HAVING CORROSION INHIBITORS THEREIN | NORTHERN TECHNOLOGIES INTERNATIONAL CORPORATION (US) | 2019-04-11 | — | — | WO | claimed |
| US-9241956-B2 | Pharmaceutical preparation and method for treatment of diabetes | TIBBS KENNETH JOHN (US) | 2016-01-26 | — | — | US | claimed |
| US-20150110881-A1 | Pharmaceutical preparation and method for treatment of diabetes | TIBBS KENNETH JOHN (US) | 2015-04-23 | — | — | US | claimed |
| EP-0725625-B1 | GELATIN CAPSULE FILL ABLE TO FOAM | SCHERER CORP R P (US) | 2000-03-22 | — | — | EP | claimed |
| US-5888540-A | Pharmaceutical products | CATALENT PHARMA SOLUTIONS, INC. | 1999-03-30 | — | — | US | claimed |
| EP-0725625-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | R.P. SCHERER CORPORATION (US) | 1996-08-14 | — | — | EP | claimed |
| EP-0725626-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1996-08-14 | — | — | EP | claimed |
| US-5480587-A | PAPER OR POLYMERS | ALUMINUM COMPANY OF AMERICA (US) | 1996-01-02 | — | — | US | claimed |
| WO-1995011667-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | R.P. SCHERER CORPORATION (US) | 1995-05-04 | — | — | WO | claimed |
| WO-1995011668-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1995-05-04 | — | — | WO | claimed |
| EP-0377881-A1 | Materials for use as fire retardant additives | ALUMINUM COMPANY OF AMERICA (US) | 1990-07-18 | — | — | EP | claimed |
| JP-61135785-A | — | — | None | — | — | JP | disclosed |
| US-12637557-B2 | High crystalline olefin polymer for high speed spinning | W.R. GRACE & CO.-CONN. (US) | 2026-05-26 | — | — | US | disclosed |
| US-4529769-A | Blend containing hydrotalcite | PHILLIPS PETROLEUM COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0147692-A1 | Poly(arylene sulfide) composition and article of manufacture | PHILLIPS PETROLEUM COMPANY (US) | 1985-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637557-B2 | High crystalline olefin polymer for high speed spinning | DYRK1B, DYRK3, TARDBP | CA4 4797/4885CA1 4531/4885FAHD1 1322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.