Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | ATF1 | P18846 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28066873 | 0.76 | HPGD (0.48) | ATF1NFKB1ESR1SMN1; SMN2HTT | |
| SCHEMBL23050262 | 0.73 | L3MBTL1 (0.39) | BCHEACHESMN1; SMN2LMNANPC1 | |
| SCHEMBL23050297 | 0.73 | L3MBTL1 (0.39) | BCHEACHESMN1; SMN2LMNANPC1 | |
| SCHEMBL23050216 | 0.73 | L3MBTL1 (0.35) | BCHEACHESMN1; SMN2LMNANPC1 | |
| SCHEMBL1489997 | 0.70 | ATF1 (0.48) | ATF1NFKB1SMN1; SMN2LMNANPC1 | |
| SCHEMBL6508740 | 0.69 | NPR3 (0.53) | CYP2C9CYP2C19 | |
| SCHEMBL6508736 | 0.69 | NPR3 (0.53) | CYP2C9CYP2C19 | |
| SCHEMBL16372124 | 0.68 | ATF1 (0.49) | ATF1NFKB1SMN1; SMN2HTTLMNA | |
| SCHEMBL10857111 | 0.67 | KMT2A (0.49) | BCHEACHESMN1; SMN2HTTNPC1 | |
| SCHEMBL5672221 | 0.66 | MAPT (0.49) | ESR1HTTLMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786166-A1 | 2-AMINOPYRIMIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | Etern Biopharma (Shanghai) Co., Ltd. (CN) | 2021-03-03 | — | — | EP | disclosed |