SCHEMBL23051242

SCHEMBL23051242

CC(C)Cc1ccc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PTGS2 P35354 2/20 0.47
PTPN1 P18031 2/20 0.47
DHODH Q02127 1/20 0.40
HDAC4 P56524 1/20 0.40
AKR1C4 P17516 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
DRD1 P21728 3/20 0.37
DRD5 P21918 3/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
ALOX5AP P20292 2/20 0.36
FAAH O00519 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23917872 0.95 KDM4E (0.53) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL25585669 0.90 KDM4E (0.44) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL19762215 0.89 KDM4E (0.46) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL13290123 0.88 KDM4E (0.46) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL24474720 0.87 PTPN1 (0.42) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL10111049 0.86 HPGD (0.45) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL13562910 0.85 PTGS2 (0.48) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL13562915 0.85 KDM4E (0.42) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL262011 0.84 PTPN1 (0.41) KDM4EATML3MBTL1PTGS2PTPN1
SCHEMBL262475 0.84 PTPN1 (0.41) KDM4EATML3MBTL1PTGS2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-06-02 US disclosed
US-20210320263-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-14 US disclosed
US-20210062081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, OR10J3 KDM4E 1293/4885ATM 2614/4885L3MBTL1 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.