Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1822139 | 0.82 | KMT2A (0.59) | KMT2AKDM4CCA12CA1CA2 | |
| SCHEMBL3363601 | 0.79 | SMN1; SMN2 (0.76) | KMT2AKDM4CCA12CA1CA2 | |
| SCHEMBL23051373 | 0.78 | MAPT (0.45) | KMT2AMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7137750 | 0.77 | MEN1 (0.72) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11892329 | 0.77 | EGFR (0.56) | KMT2AKDM4CCA12CA1CA2 | |
| SCHEMBL5943429 | 0.77 | KMT2A (0.56) | KMT2AKDM4CCA12CA1CA2 | |
| SCHEMBL11892327 | 0.77 | HDAC3 (0.66) | KMT2AEGFR | |
| SCHEMBL11929757 | 0.77 | NLRP3 (0.58) | KMT2AKDM4CEGFRMEN1NPC1 | |
| SCHEMBL11195217 | 0.77 | KMT2A (0.56) | KMT2AKDM4CCA1CA2EGFR | |
| SCHEMBL23796819 | 0.76 | SMN1; SMN2 (0.58) | KMT2AKDM4CCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021036793-A1 | PYROPTOSIS-INDUCED IMMUNOTHERAPY | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-03-04 | — | — | WO | disclosed |