Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051998 | 0.78 | TDP1 (0.75) | L3MBTL1TDP1ALDH1A1ALOX15HTT | |
| SCHEMBL23045594 | 0.74 | TDP1 (0.72) | L3MBTL1TDP1ALDH1A1ALOX15HTT | |
| SCHEMBL16221401 | 0.73 | TDP1 (0.76) | L3MBTL1TDP1ALDH1A1ALOX15NPSR1 | |
| SCHEMBL7217749 | 0.73 | CYP2D6 (0.72) | CYP2D6CYP2C9CYP2C19TDP1ALDH1A1 | |
| SCHEMBL23052287 | 0.72 | TDP1 (0.65) | L3MBTL1TDP1ALDH1A1ALOX15HTT | |
| SCHEMBL6127516 | 0.72 | CYP2D6 (0.82) | L3MBTL1CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6127693 | 0.72 | CYP2D6 (0.82) | L3MBTL1CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23023146 | 0.71 | TP53 (0.48) | L3MBTL1ALDH1A1ALOX15HTTKDM4E | |
| SCHEMBL7194116 | 0.70 | CYP2D6 (0.79) | L3MBTL1CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5652601 | 0.70 | CYP2D6 (0.79) | L3MBTL1CYP2D6CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |