Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051998 | 0.84 | TDP1 (0.75) | TDP1ALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL23045594 | 0.82 | TDP1 (0.72) | TDP1ALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL16221401 | 0.79 | TDP1 (0.76) | TDP1ALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL10144085 | 0.78 | TDP1 (0.62) | TDP1ALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL23052368 | 0.76 | TDP1 (0.70) | TDP1ALDH1A1HTTLMNAL3MBTL1 | |
| SCHEMBL9927443 | 0.76 | TPSAB1 (0.67) | ALDH1A1HSD17B10 | |
| SCHEMBL23052427 | 0.74 | TDP1 (0.67) | TDP1ALDH1A1HTTL3MBTL1TSHR | |
| SCHEMBL9895381 | 0.74 | TPSAB1 (0.65) | ALDH1A1GAATP53 | |
| SCHEMBL6290158 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL23052527 | 0.73 | TDP1 (0.66) | TDP1ALDH1A1HTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |