Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23045594 | 0.92 | TDP1 (0.72) | TDP1L3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL16221401 | 0.86 | TDP1 (0.76) | TDP1L3MBTL1ALDH1A1KMT2AALOX15 | |
| SCHEMBL23052287 | 0.84 | TDP1 (0.65) | TDP1L3MBTL1ALDH1A1HTTALOX15 | |
| SCHEMBL23052368 | 0.82 | TDP1 (0.70) | TDP1L3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL23052427 | 0.80 | TDP1 (0.67) | TDP1L3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL23052527 | 0.79 | TDP1 (0.66) | TDP1L3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL23052016 | 0.78 | L3MBTL1 (0.60) | TDP1L3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL10144085 | 0.77 | TDP1 (0.62) | TDP1L3MBTL1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL8349568 | 0.73 | ALDH1A1 (0.79) | TDP1ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL12601567 | 0.73 | ALDH1A1 (0.69) | TDP1L3MBTL1ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |