Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052297 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL3816280 | 0.81 | USP30 (0.58) | ALDH1A1 | |
| SCHEMBL4215483 | 0.79 | SMN1; SMN2 (0.44) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL15308195 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1LMNADUSP3 | |
| SCHEMBL15882764 | 0.71 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1DUSP3PTPN5 | |
| SCHEMBL16000103 | 0.71 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL2804229 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1LMNADUSP3 | |
| SCHEMBL6867265 | 0.69 | KMT5B (0.53) | ALDH1A1KMT2AMEN1CYP2C19CASP6 | |
| SCHEMBL6867268 | 0.69 | KMT5B (0.53) | ALDH1A1KMT2AMEN1CYP2C19CASP6 | |
| SCHEMBL12774648 | 0.69 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |