Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 11/20 | 0.58 |
| ▸ | UCHL1 | P09936 | 11/20 | 0.58 |
| ▸ | CTSB | P07858 | 6/20 | 0.56 |
| ▸ | CTSK | P43235 | 6/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.56 |
| ▸ | CTSC | P53634 | 4/20 | 0.56 |
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052040 | 0.81 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL3806662 | 0.79 | ALDH1A1 (0.62) | USP30UCHL1CTSBCTSKCTSS | |
| SCHEMBL23052297 | 0.79 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL3813822 | 0.76 | USP30 (0.67) | USP30UCHL1CTSBCTSKCTSS | |
| SCHEMBL3815942 | 0.76 | USP30 (0.71) | USP30UCHL1CTSBCTSKCTSS | |
| SCHEMBL3810609 | 0.76 | CTSB (0.74) | USP30UCHL1CTSBCTSKCTSS | |
| SCHEMBL3811344 | 0.76 | USP30 (0.70) | USP30UCHL1CTSBCTSKCTSS | |
| SCHEMBL3806556 | 0.76 | USP30 (0.70) | USP30UCHL1CTSBCTSKCTSS | |
| SCHEMBL3806187 | 0.76 | CTSB (0.74) | USP30UCHL1CTSBCTSKCTSS | |
| SCHEMBL3806512 | 0.76 | USP30 (0.70) | USP30UCHL1CTSBCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129370-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (US) | 2009-10-22 | — | — | WO | claimed |
| WO-2009129370-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (US) | 2009-10-22 | — | — | WO | disclosed |