Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052541 | 0.83 | KDM4E (0.73) | LMNAMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL14541099 | 0.76 | GPR55 (0.74) | LMNAMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL14541097 | 0.73 | PRKCZ (0.68) | LMNAMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL14541143 | 0.72 | KMT2A (0.70) | LMNAKDM4EKMT2ANPSR1HPGD | |
| SCHEMBL5303942 | 0.70 | GPR55 (0.69) | LMNAKDM4EKMT2ANPSR1HPGD | |
| SCHEMBL14540783 | 0.70 | KMT2A (0.64) | LMNAKDM4EKMT2ANPSR1HPGD | |
| SCHEMBL14541111 | 0.70 | KMT2A (0.62) | LMNAMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL23052519 | 0.70 | GPR55 (0.77) | LMNAKDM4EKMT2AHPGDHTT | |
| SCHEMBL14132789 | 0.70 | KMT2A (0.72) | LMNAMAPTKDM4EKMT2ANPSR1 | |
| SCHEMBL14541086 | 0.69 | KMT2A (0.65) | LMNAMAPTKDM4EKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |