Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 5/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052781 | 0.83 | MME (0.46) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL21451346 | 0.83 | MME (0.46) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL21451281 | 0.83 | MME (0.46) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL22628802 | 0.80 | GRN (0.38) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL22487801 | 0.76 | TGFBR1 (0.47) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL30925323 | 0.76 | TGFBR1 (0.39) | TGFBR1MMEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL5712806 | 0.74 | TGFBR1 (0.42) | TGFBR1MMEALDH1A1LMNA | |
| SCHEMBL5712807 | 0.74 | TGFBR1 (0.42) | TGFBR1MMEALDH1A1LMNA | |
| SCHEMBL8934132 | 0.73 | TGFBR1 (0.41) | TGFBR1MMEALDH1A1MAPT | |
| SCHEMBL1960483 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210061755-A1 | AROMATIC VINYL OR AROMATIC ETHYL DERIVATIVE, PREPARATION METHOD THEREFOR, INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061755-A1 | AROMATIC VINYL OR AROMATIC ETHYL DERIVATIVE, PREPARATION METHOD THEREFOR, INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION | PDCD1, CD274, PDCD1LG2 | TGFBR1 47/4885MME 4094/4885FOLH1 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.