Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.36 |
| ▸ | MME | P08473 | 5/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052826 | 0.80 | TGFBR1 (0.41) | TGFBR1MMEMAPTFOLH1NAALAD2 | |
| SCHEMBL21451281 | 0.75 | MME (0.46) | TGFBR1MMEMAPTFOLH1NAALAD2 | |
| SCHEMBL21451346 | 0.75 | MME (0.46) | TGFBR1MMEMAPTFOLH1NAALAD2 | |
| SCHEMBL23052781 | 0.75 | MME (0.46) | TGFBR1MMEMAPTFOLH1NAALAD2 | |
| SCHEMBL18822312 | 0.70 | CTSS (0.44) | GRNSORT1TGFBR1MMEPDCD1 | |
| SCHEMBL22487801 | 0.69 | TGFBR1 (0.47) | TGFBR1MMEPDCD1CD274MAPT | |
| SCHEMBL30925323 | 0.69 | TGFBR1 (0.39) | TGFBR1MMEMAPTFOLH1NAALAD2 | |
| SCHEMBL13395755 | 0.68 | TSHR (0.37) | — | |
| SCHEMBL13395757 | 0.68 | TSHR (0.37) | — | |
| SCHEMBL13395730 | 0.68 | TSHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3733659-A1 | AROMATIC VINYL OR AROMATIC ETHYL DERIVATIVE, PREPARATION METHOD THEREFOR, INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION | Guangzhou Maxinovel Pharmaceuticals Co., Ltd. (CN) | 2020-11-04 | — | — | EP | disclosed |