Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLQ | O75417 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055021 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL23054779 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL23055031 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL23054777 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL15480457 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL27351408 | 0.87 | CES2 (0.50) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL1114949 | 0.87 | HDAC6 (0.50) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL15480456 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL4130517 | 0.86 | NPC1 (0.53) | ALDH1A1KDM4ELMNAPOLBKMT2A | |
| SCHEMBL10407826 | 0.86 | NPC1 (0.53) | ALDH1A1KDM4ELMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB (SE) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | ALDH1A1 3068/4885KDM4E 330/4885LMNA 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.