SCHEMBL23055201

SCHEMBL23055201

CN1C(=O)c2ccc(C(=O)Oc3ccc(-c4ccc(OC(=O)c5ccc6c(c5)C(=O)NC6=O)cc4)cc3)cc2C1=O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47
ALDH1A1 P00352 7/20 0.43
KMT2A Q03164 6/20 0.43
MEN1 O00255 5/20 0.43
CTDSP1 Q9GZU7 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 1/20 0.40
APP P05067 1/20 0.39
CASP3 P42574 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24034831 0.95 FNTA (0.48) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL19755147 0.92 FNTA (0.52) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL19755136 0.89 KMT2A (0.47) FNTAFNTBKMT2AMEN1CTDSP1
SCHEMBL19755146 0.88 FNTA (0.55) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL19755129 0.85 KMT2A (0.50) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL23055339 0.85 FNTA (0.43) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL23055200 0.85 FNTA (0.43) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL24710682 0.85 FNTA (0.46) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL24034918 0.84 KMT2A (0.48) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL23055337 0.84 LMNA (0.43) FNTAFNTBALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834598-B2 Dielectric copolymer materials MERCK PATENT GMBH (DE) 2023-12-05 US disclosed
US-20210355381-A1 DIELECTRIC COPOLYMER MATERIALS MERCK PATENT GMBH (DE) 2021-11-18 US disclosed
US-20210062091-A1 DIELECTRIC MATERIALS MERCK PATENT GMBH (DE) 2021-03-04 US disclosed