SCHEMBL24710682

SCHEMBL24710682

BN1C(=O)c2ccc(C(=O)Oc3ccc(OC(=O)c4ccc5c(c4)C(=O)NC5=O)cc3)cc2C1=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
ALDH1A1 P00352 4/20 0.45
KMT2A Q03164 7/20 0.41
MEN1 O00255 5/20 0.41
CTDSP1 Q9GZU7 1/20 0.40
MAOA P21397 4/20 0.38
MAOB P27338 4/20 0.38
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19755129 0.87 KMT2A (0.50) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL24034831 0.87 FNTA (0.48) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL23055201 0.85 FNTA (0.47) FNTAFNTBALDH1A1KMT2AMEN1
SCHEMBL19755136 0.83 KMT2A (0.47) FNTAFNTBKMT2AMEN1CTDSP1
SCHEMBL19755139 0.81 MAOA (0.60) KMT2AMEN1CTDSP1MAOAMAOB
SCHEMBL2244159 0.80 MAOA (0.55) ALDH1A1KMT2AMEN1CTDSP1MAOA
SCHEMBL19755123 0.80 GRM5 (0.51) FNTAFNTBKMT2AMEN1CTDSP1
SCHEMBL19755141 0.80 PRSS1 (0.44) KMT2AMEN1CTDSP1MAOAMAOB
SCHEMBL19755138 0.80 KMT2A (0.54) KMT2AMEN1CTDSP1MAOAMAOB
SCHEMBL19755146 0.79 FNTA (0.55) FNTAFNTBALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022261654-A1 OPTICALLY TRANSPARENT POLYIMIDE ZYMERGEN INC. (US) 2022-12-15 WO disclosed