SCHEMBL2305550

SCHEMBL2305550

NP(N)(=O)N(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8698241 0.67
SCHEMBL11147635 0.67
SCHEMBL440940 0.64
SCHEMBL454419 0.64
SCHEMBL4737874 0.64
SCHEMBL19348645 0.64
SCHEMBL440939 0.64
SCHEMBL6688533 0.62
SCHEMBL50123 0.61
SCHEMBL17004026 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138964-A1 PREPARATION OF PHENETHYLAMINES AND CATHINONES AND STEREOISOMERS THEREOF AND PRECURSORS THEREOF TRANSCEND THERAPEUTICS, INC. (US) 2026-05-21 US disclosed
US-20250270242-A1 PHENETHYLAMINES AND CATHINONES PRECURSORS TRANSCEND THERAPEUTICS, INC. (US) 2025-08-28 US disclosed
EP-4605385-A1 PREPARATION OF PHENETHYLAMINES AND CATHINONES AND STEREOISOMERS THEREOF AND PRECURSORS THEREOF Transcend Therapeutics, Inc. (US) 2025-08-27 EP disclosed
EP-4573084-A1 PHENETHYLAMINES AND CATHINONES PRECURSORS Transcend Therapeutics, Inc. (US) 2025-06-25 EP disclosed
US-12297220-B2 Phenethylamines and cathinones precursors TRANSCEND THERAPEUTICS, INC. (US) 2025-05-13 US disclosed
US-20250129108-A1 PHENETHYLAMINES AND CATHINONES PRECURSORS TRANSCEND THERAPEUTICS, INC. (US) 2025-04-24 US disclosed
US-20240374558-A1 PREPARATION OF PHENETHYLAMINES AND CATHINONES AND STEREOISOMERS THEREOF AND PRECURSORS THEREOF TRANSCEND THERAPEUTICS, INC. (US) 2024-11-14 US disclosed
WO-2024039599-A9 PHENETHYLAMINES AND CATHINONES PRECURSORS TRANSCEND THERAPEUTICS, INC. (US) 2024-10-31 WO disclosed
US-20240327372-A1 PREPARATION OF PHENETHYLAMINES AND CATHINONES AND STEREOISOMERS THEREOF AND PRECURSORS THEREOF TRANSCEND THERAPEUTICS, INC. (US) 2024-10-03 US disclosed
WO-2024086218-A1 PREPARATION OF PHENETHYLAMINES AND CATHINONES AND STEREOISOMERS THEREOF AND PRECURSORS THEREOF TRANSCEND THERAPEUTICS, INC. (US) 2024-04-25 WO disclosed
CN-101648977-B 2,2',6,6'site connected 1,1'-diphenyl axially chiral bi-phosphoramide and phosphorous acid ester ligand and preparation method thereof UNIV SHANGHAI JIAOTONG 2013-04-24 CN disclosed
CN-102395590-A Purine nucleoside monophosphate prodrugs for treatment of cancer and viral infections RFS PHARMA LLC 2012-03-28 CN disclosed
EP-2351844-A1 Compositions for enhancing transport and antisense efficacy of nucleic acid analog into cells AVI BioPharma, Inc. (US) 2011-08-03 EP disclosed
EP-1629105-B1 COMPOSITIONS FOR ENHANCING TRANSPORT AND ANTISENSE EFFICACY OF NUCLEIC ACID ANALOG INTO CELLS AVI BIOPHARMA INC (US) 2010-09-01 EP disclosed
CN-101648977-A 2,2',6,6'site connected 1,1'-diphenyl axially chiral bi-phosphoramide and phosphorous acid ester ligand and preparation method thereof UNIV SHANGHAI JIAOTONG 2010-02-17 CN disclosed
US-20090082547-A1 COMPOSITIONS FOR ENHANCING TRANSPORT OF MOLECULES INTO CELLS SAREPTA THERAPEUTICS, INC. 2009-03-26 US disclosed
US-7468418-B2 peptide nucleic acid conjugate of a nucleic acid analog covalently linked to a peptide transporter moiety; enhance antisense activity; drug delivery; conjugate is a morpholino-base with phosphorodiamidate linkages with a peptide such as Arg9Phe2 (arginine9phenylalanine2) AVI BIOPHARMA., INC. (US) 2008-12-23 US disclosed
EP-1629105-A2 COMPOSITIONS FOR ENHANCING TRANSPORT AND ANTISENSE EFFICACY OF NUCLEIC ACID ANALOG INTO CELLS Avi Biopharma, Inc. (US) 2006-03-01 EP disclosed
US-20040265879-A1 peptide nucleic acid conjugate of a nucleic acid analog covalently linked to a peptide transporter moiety; enhance antisense activity; drug delivery; conjugate is a morpholino-base with phosphorodiamidate linkages with a peptide such as Arg9Phe2 (arginine9phenylalanine2) SAREPTA THERAPEUTICS, INC. 2004-12-30 US disclosed
WO-2004097017-A2 COMPOSITIONS FOR ENHANCING TRANSPORT AND ANTISENSE EFFICACY OF NUCLEIC ACID ANALOG INTO CELLS AVI BIOPHARMA, INC. (US) 2004-11-11 WO disclosed