Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21526161 | 0.89 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL21526160 | 0.89 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL31016975 | 0.89 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL21553419 | 0.89 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL21526162 | 0.88 | CNR1 (0.67) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL21526163 | 0.88 | CNR1 (0.67) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL24486720 | 0.88 | CYP1A2 (0.75) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL21526174 | 0.88 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL21526173 | 0.88 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL31016972 | 0.88 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210061830-A1 | MITO-LONIDAMINE, COMPOSITIONS AND METHODS OF USE | AIX-MARSEILLE UNIVERSITE (FR) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061830-A1 | MITO-LONIDAMINE, COMPOSITIONS AND METHODS OF USE | COX5B, COX5A, LONP1 | CYP1A2 613/4885CYP3A4 807/4885CYP2C9 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.