Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.39 |
| ▸ | PPARG | P37231 | 9/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23056600 | 0.90 | CYP1A2 (0.38) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL23056299 | 0.89 | PPARA (0.40) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL16310609 | 0.89 | PPARA (0.42) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL16289575 | 0.85 | PPARA (0.38) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL16289576 | 0.85 | PPARA (0.38) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL16289577 | 0.85 | PPARA (0.38) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL23056456 | 0.83 | CTSS (0.41) | CTSSCTSKCTSLCTSBCYP1A2 | |
| SCHEMBL29539768 | 0.79 | CTSK (0.46) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL15083192 | 0.79 | CYP1A2 (0.38) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL23056579 | 0.79 | CYP1A2 (0.38) | PPARAPPARGCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | PPARA 3215/4885PPARG 3973/4885CTSS 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.