Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834586 | 0.87 | ALDH1A1 (0.75) | ALDH1A1KEAP1TSHRPKMMEN1 | |
| SCHEMBL4623054 | 0.87 | ALDH1A1 (0.75) | ALDH1A1KEAP1TSHRMEN1KMT2A | |
| SCHEMBL1116405 | 0.87 | ALDH1A1 (0.74) | ALDH1A1KEAP1TSHRMEN1KMT2A | |
| SCHEMBL30102910 | 0.87 | ALDH1A1 (0.74) | ALDH1A1KEAP1TSHRMEN1KMT2A | |
| SCHEMBL3081594 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KEAP1TSHRPKMMEN1 | |
| SCHEMBL1592863 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KEAP1TSHRMEN1KMT2A | |
| SCHEMBL13875339 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KEAP1TSHRMEN1KMT2A | |
| SCHEMBL2240809 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KEAP1TSHRPKMMEN1 | |
| SCHEMBL31681420 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KEAP1TSHRMEN1KMT2A | |
| SCHEMBL7562043 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KEAP1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041866-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |