SCHEMBL23057562

SCHEMBL23057562

C/C(=N/O)C(C)(C)NCCC(CCNC(=O)CCCC(=O)NCCCC[C@@H]1NC(=O)CSCC(C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CS)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC1=O)CCNC(C)(C)/C(C)=N\O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TSLP Q969D9 12/20 0.47
▸ GRB7 Q14451 1/20 0.44
▸ MC4R P32245 3/20 0.44
▸ MC5R P33032 3/20 0.44
▸ MC3R P41968 3/20 0.44
▸ MC1R Q01726 3/20 0.44
▸ CTSG P08311 2/20 0.44
▸ ITGB3 P05106 2/20 0.44
▸ ITGB1 P05556 2/20 0.44
▸ ITGAV P06756 2/20 0.44
▸ ITGA5 P08648 2/20 0.44
▸ ITGB5 P18084 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10052624 1.00 TSLP (0.47) TSLPGRB7MC4RMC5RMC3R
SCHEMBL10046409 1.00 TSLP (0.47) TSLPGRB7MC4RMC5RMC3R
SCHEMBL22003312 1.00 TSLP (0.47) TSLPGRB7MC4RMC5RMC3R
SCHEMBL12353621 0.94 TSLP (0.50) TSLPGRB7MC4RMC5RMC3R
SCHEMBL13887745 0.94 MC4R (0.44) TSLPMC4RMC5RMC3RMC1R
SCHEMBL16326787 0.92 ITGB3 (0.45) TSLPMC4RMC5RMC3RMC1R
SCHEMBL16349760 0.92 MC4R (0.47) TSLPGRB7MC4RMC5RMC3R
SCHEMBL13887996 0.91 ITGB3 (0.49) TSLPMC4RMC5RMC3RMC1R
SCHEMBL20809940 0.91 ITGB3 (0.49) TSLPMC4RMC5RMC3RMC1R
SCHEMBL12462751 0.91 ITGB3 (0.49) TSLPMC4RMC5RMC3RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723991-B2 Radiopharmaceutical compositions SERAC HEALTHCARE LIMITED (GB) 2023-08-15 — — US disclosed
US-20210060189-A1 RADIOPHARMACEUTICAL COMPOSITIONS SERAC HEALTHCARE LIMITED (GB) 2021-03-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11723991-B2 Radiopharmaceutical compositions TYMP, KIT, CHEK1 TSLP 329/4885GRB7 1916/4885MC4R 576/4885
US-20210060189-A1 RADIOPHARMACEUTICAL COMPOSITIONS TYMP, KIT, CHEK1 TSLP 329/4885GRB7 1916/4885MC4R 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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