Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 11/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30062927 | 1.00 | EIF2AK3 (0.45) | EIF2AK3RIPK2METAXLDYRK1A | |
| SCHEMBL20351612 | 0.81 | MET (0.41) | EIF2AK3RIPK2METAXLDYRK1A | |
| SCHEMBL20351783 | 0.81 | RIPK2 (0.61) | EIF2AK3RIPK2METAXL | |
| SCHEMBL30060920 | 0.80 | DYRK1A (0.40) | EIF2AK3METAXLDYRK1ARIPK1 | |
| SCHEMBL23057767 | 0.78 | DYRK1A (0.39) | EIF2AK3RIPK2METAXLDYRK1A | |
| SCHEMBL30060936 | 0.78 | DYRK1A (0.39) | EIF2AK3RIPK2METAXLDYRK1A | |
| SCHEMBL19684546 | 0.76 | DYRK1A (0.41) | EIF2AK3METAXLDYRK1A | |
| SCHEMBL23059956 | 0.74 | EIF2AK3 (0.46) | EIF2AK3METAXLRIPK1 | |
| SCHEMBL20351752 | 0.73 | RIPK2 (0.48) | EIF2AK3RIPK2METAXL | |
| Hydrochloric Acid SCHEMBL29911616 | 0.73 | EIF2AK3 (0.45) | EIF2AK3METAXLRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041975-A1 | PERK INHIBITING PYRROLOPYRIMIDINE COMPOUNDS | HIBERCELL, INC. (US) | 2021-03-04 | — | — | WO | disclosed |