Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24454293 | 0.79 | HDAC3 (0.40) | OPRM1 | |
| SCHEMBL15723317 | 0.79 | CCR2 (0.38) | TACR1TACR3CCR2KCNH2 | |
| SCHEMBL23113569 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL22497913 | 0.78 | NOTUM (0.44) | — | |
| SCHEMBL21610788 | 0.78 | CCR2 (0.34) | TACR1TACR3CCR2KCNH2 | |
| SCHEMBL29659847 | 0.78 | NOTUM (0.44) | — | |
| SCHEMBL24454611 | 0.74 | CCR2 (0.35) | TACR1CCR2OPRM1 | |
| SCHEMBL21610790 | 0.73 | CCR2 (0.33) | TACR1TACR3CCR2 | |
| SCHEMBL21610813 | 0.73 | CCR2 (0.36) | TACR1TACR3CCR2 | |
| SCHEMBL10629252 | 0.73 | TACR1 (0.39) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143596-A1 | PESTICIDALLY ACTIVE DIAZINE-BISAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20230143596-A1 | PESTICIDALLY ACTIVE DIAZINE-BISAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20220159958-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-26 | — | — | US | disclosed |
| WO-2021037614-A1 | PESTICIDALLY ACTIVE PYRAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143596-A1 | PESTICIDALLY ACTIVE DIAZINE-BISAMIDE COMPOUNDS | DDT, ACHE, NIT2 | TACR1 2209/4885TACR3 709/4885CCR2 4467/4885 |
| US-20220159958-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | TACR1 1874/4885TACR3 296/4885CCR2 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.