Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ACVR2A | P27037 | 3/20 | 0.38 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18755256 | 0.81 | LOX (0.45) | LOXLOXL2LRRK2S1PR1PKN1 | |
| SCHEMBL15720549 | 0.80 | PDCD1 (0.48) | LOXLOXL2LRRK2PKN1PKN2 | |
| SCHEMBL25203368 | 0.80 | PDCD1 (0.43) | LOXLOXL2LRRK2S1PR1PKN1 | |
| SCHEMBL30042559 | 0.78 | IDO1 (0.48) | LOXLOXL2LRRK2CYP19A1ATR | |
| SCHEMBL2713579 | 0.76 | LRRK2 (0.46) | LOXLOXL2LRRK2S1PR1PKN1 | |
| SCHEMBL20119880 | 0.76 | CYP3A4 (0.48) | LOXLOXL2LRRK2S1PR1CNR1 | |
| SCHEMBL30469293 | 0.76 | MAP4K4 (0.49) | LOXLOXL2LRRK2PKN1PKN2 | |
| SCHEMBL20557310 | 0.76 | MAP4K4 (0.49) | LOXLOXL2LRRK2PKN1PKN2 | |
| SCHEMBL30626327 | 0.75 | LOX (0.55) | LOXLOXL2LRRK2S1PR1CNR1 | |
| SCHEMBL16116782 | 0.75 | LOX (0.55) | LOXLOXL2LRRK2S1PR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533913-A | Novel compounds | 英夫拉索姆有限公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-3788041-A1 | NOVEL COMPOUNDS | Inflazome Limited (IE) | 2021-03-10 | — | — | EP | disclosed |