Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.79 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Buparvaquone SCHEMBL11030015 | 0.97 | CDC25B (0.82) | CDC25BAPAF1TDP2GLAPOLB | |
| Buparvaquone SCHEMBL30634020 | 0.97 | CDC25B (0.82) | CDC25BAPAF1TDP2GLAPOLB | |
| Buparvaquone SCHEMBL21863689 | 0.97 | CDC25B (0.82) | CDC25BAPAF1TDP2GLAPOLB | |
| Buparvaquone SCHEMBL22978 | 0.97 | CDC25B (0.82) | CDC25BAPAF1TDP2GLAPOLB | |
| Buparvaquone SCHEMBL9598809 | 0.97 | CDC25B (0.82) | CDC25BAPAF1TDP2GLAPOLB | |
| Buparvaquone SCHEMBL18740425 | 0.91 | CDC25B (0.73) | CDC25BAPAF1TDP2GLAPOLB | |
| SCHEMBL28771087 | 0.88 | CDC25B (1.00) | CDC25BAPAF1TDP2GLAPOLB | |
| Buparvaquone SCHEMBL8200585 | 0.86 | CDC25B (0.66) | CDC25BAPAF1TDP2GLAPOLB | |
| SCHEMBL11066448 | 0.86 | CDC25B (0.65) | CDC25BAPAF1TDP2POLBRAB9A | |
| SCHEMBL11066443 | 0.86 | CDC25B (0.65) | CDC25BAPAF1TDP2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130832-A1 | METHODS OF GENE THERAPY | OREGON HEALTH & SCIENCE UNIVERSITY | 2021-05-06 | — | — | US | claimed |
| EP-3787693-A1 | METHODS OF GENE THERAPY | Oregon Health & Science University (US) | 2021-03-10 | — | — | EP | claimed |
| US-20210130832-A1 | METHODS OF GENE THERAPY | OREGON HEALTH & SCIENCE UNIVERSITY | 2021-05-06 | — | — | US | disclosed |
| EP-3787693-A1 | METHODS OF GENE THERAPY | Oregon Health & Science University (US) | 2021-03-10 | — | — | EP | disclosed |