Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21737827 | 0.84 | MAP4K1 (0.47) | MAP4K1 | |
| SCHEMBL20803415 | 0.78 | ASIC3 (0.38) | MAP4K1ASIC3MAP3K5 | |
| SCHEMBL21964139 | 0.78 | MAP4K1 (0.48) | MAP4K1 | |
| SCHEMBL23865142 | 0.77 | NOS3 (0.40) | ASIC3METAP2CSNK1ECLK1CLK2 | |
| SCHEMBL20802870 | 0.76 | MAP4K1 (0.36) | MAP4K1ASIC3MAP3K5 | |
| SCHEMBL20472682 | 0.75 | TLR8 (0.47) | MAP4K1 | |
| SCHEMBL20802727 | 0.75 | MAP4K1 (0.36) | MAP4K1ASIC3MAP3K5 | |
| SCHEMBL20803015 | 0.75 | MAP4K1 (0.36) | MAP4K1ASIC3 | |
| SCHEMBL22474000 | 0.73 | ASIC3 (0.41) | MAP4K1ASIC3CDK9DYRK1ADYRK2 | |
| SCHEMBL21724058 | 0.72 | MAP3K5 (0.52) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407806-B | Carboxamide compounds, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| US-20210139454-A1 | FORMAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2021-05-13 | — | — | US | disclosed |
| US-20210139454-A1 | FORMAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2021-05-13 | — | — | US | disclosed |
| EP-3789384-A1 | FORMAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2021-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139454-A1 | FORMAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | WEE1, WEE2, MAP3K11 | MAP4K1 48/4885ASIC3 2749/4885METAP2 1742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.