Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.36 |
| ▸ | WNT3A | P56704 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25674678 | 0.81 | OPRL1 (0.37) | OPRL1HDAC3HDAC1ADRA1APTGDR2 | |
| Hydrochloric Acid SCHEMBL25211506 | 0.79 | OPRL1 (0.36) | OPRL1HDAC3HDAC1ADRA1APTGDR2 | |
| SCHEMBL6383642 | 0.78 | ADRA1A (0.51) | OPRL1ADRA1ACTNNB1HSD17B10KDM4E | |
| SCHEMBL28212021 | 0.78 | ADRA1A (0.51) | OPRL1ADRA1ACTNNB1HSD17B10KDM4E | |
| SCHEMBL161548 | 0.78 | ADRA1A (0.51) | OPRL1ADRA1ACTNNB1HSD17B10KDM4E | |
| SCHEMBL10690998 | 0.78 | PTGDR2 (0.52) | HDAC3HDAC1PTGDR2CYP2D6SLC6A2 | |
| SCHEMBL25213301 | 0.77 | PTPN1 (0.49) | OPRL1PTGDR2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL19566113 | 0.77 | HCRTR1 (0.41) | PTGDR2HCRTR2HCRTR1KDM4E | |
| Hydrochloric Acid SCHEMBL30170745 | 0.77 | ADRA1A (0.50) | OPRL1ADRA1ACTNNB1HSD17B10KDM4E | |
| SCHEMBL7047667 | 0.75 | ADRA1A (0.39) | OPRL1ADRA1APTGDR2CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788042-A1 | BCL-2 INHIBITORS | BeiGene, Ltd. (KY) | 2021-03-10 | — | — | EP | disclosed |