Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 20/20 | 1.00 |
| ▸ | TRPC3 | Q13507 | 15/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550532 | 1.00 | TRPC6 (1.00) | TRPC6TRPC3KCNH2 | |
| SCHEMBL21563723 | 0.88 | TRPC6 (1.00) | TRPC6TRPC3KCNH2 | |
| SCHEMBL30355190 | 0.88 | TRPC6 (1.00) | TRPC6TRPC3KCNH2 | |
| SCHEMBL21550598 | 0.88 | TRPC6 (1.00) | TRPC6TRPC3KCNH2 | |
| SCHEMBL30355262 | 0.86 | TRPC3 (0.75) | TRPC6TRPC3 | |
| SCHEMBL21550361 | 0.80 | TRPC3 (1.00) | TRPC6TRPC3 | |
| SCHEMBL23068167 | 0.80 | TRPC3 (1.00) | TRPC6TRPC3 | |
| SCHEMBL23068130 | 0.76 | TRPC3 (1.00) | TRPC6TRPC3 | |
| SCHEMBL21550530 | 0.76 | TRPC3 (1.00) | TRPC6TRPC3 | |
| SCHEMBL21550297 | 0.76 | TRPC3 (1.00) | TRPC6TRPC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12378218-B2 | Cyclopentane compounds | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2025-08-05 | — | — | US | claimed |
| CN-112424182-B | Cyclopentane compounds | 迪哲(江苏)医药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| US-20220194922-A1 | CYCLOPENTANE COMPOUNDS | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2022-06-23 | — | — | US | claimed |
| WO-2021079962-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF HEARING LOSS | 国立大学法人大阪大学 | 2021-04-29 | — | — | WO | claimed |
| US-20210070733-A1 | CYCLOPENTANE COMPOUNDS | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2021-03-11 | — | — | US | claimed |
| CN-112424182-A | Cyclopentane compounds | 迪哲(江苏)医药股份有限公司 | 2021-02-26 | — | — | CN | claimed |
| US-12378218-B2 | Cyclopentane compounds | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2025-08-05 | — | — | US | disclosed |
| CN-112424182-B | Cyclopentane compounds | 迪哲(江苏)医药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20220194922-A1 | CYCLOPENTANE COMPOUNDS | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2022-06-23 | — | — | US | disclosed |
| US-11274091-B2 | Cyclopentane compounds | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-03-15 | — | — | US | disclosed |
| WO-2021079962-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF HEARING LOSS | 国立大学法人大阪大学 | 2021-04-29 | — | — | WO | disclosed |
| US-20210070733-A1 | CYCLOPENTANE COMPOUNDS | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2021-03-11 | — | — | US | disclosed |
| US-20210070733-A1 | CYCLOPENTANE COMPOUNDS | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2021-03-11 | — | — | US | disclosed |
| CN-112424182-A | Cyclopentane compounds | 迪哲(江苏)医药股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378218-B2 | Cyclopentane compounds | CYP11B2, CYP11B1, SQLE | TRPC6 3706/4885TRPC3 3056/4885KCNH2 1864/4885 |
| US-20220194922-A1 | CYCLOPENTANE COMPOUNDS | CYP11B2, CYP11B1, SQLE | TRPC6 3706/4885TRPC3 3056/4885KCNH2 1864/4885 |
| US-11274091-B2 | Cyclopentane compounds | CYP11B2, CYP11B1, SQLE | TRPC6 3706/4885TRPC3 3056/4885KCNH2 1864/4885 |
| US-20210070733-A1 | CYCLOPENTANE COMPOUNDS | CYP11B2, CYP11B1, CYP51A1 | TRPC6 3415/4885TRPC3 2969/4885KCNH2 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.