Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 11/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872865 | 1.00 | PDE1B (0.50) | PDE1BCNR1CNR2PDE5ACSF1R | |
| SCHEMBL1592906 | 0.89 | PDE1B (0.55) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL29873478 | 0.88 | CNR1 (0.43) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL23069175 | 0.88 | CNR1 (0.43) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL29872986 | 0.87 | CNR2 (0.45) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL1592961 | 0.85 | PDE1B (0.53) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL16536339 | 0.83 | PDE1B (0.51) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL1585706 | 0.83 | PDE1B (0.57) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL29872618 | 0.83 | CNR1 (0.39) | PDE1BCNR1CNR2PDE5AALDH1A1 | |
| SCHEMBL2966796 | 0.82 | PDE1B (0.55) | PDE1BCNR1CNR2PDE5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4025570-A1 | HYDANTOIN DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2022-07-13 | — | — | EP | disclosed |
| WO-2021043245-A1 | HYDANTOIN DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-03-11 | — | — | WO | disclosed |