Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29873129 | 0.86 | MAPT (0.46) | CNR1CNR2PDE5AMAPTLMNA | |
| SCHEMBL23069175 | 0.83 | CNR1 (0.43) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29872929 | 0.83 | NPBWR1 (0.43) | CNR1CNR2PDE5ABTKNPBWR1 | |
| SCHEMBL29873478 | 0.83 | CNR1 (0.43) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29872865 | 0.83 | PDE1B (0.50) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29872986 | 0.83 | CNR2 (0.45) | CNR1CNR2PDE5AMAPTALDH1A1 | |
| SCHEMBL23069164 | 0.83 | PDE1B (0.50) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29872989 | 0.82 | BUB1 (0.40) | CNR1CNR2PDE5AMAPTALDH1A1 | |
| SCHEMBL29873329 | 0.78 | NPBWR1 (0.37) | PDE5ANPBWR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1593023 | 0.78 | CNR1 (0.47) | CNR1CNR2PDE5ANPBWR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306640-A1 | HYDANTOIN DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306640-A1 | HYDANTOIN DERIVATIVE | DDR1, DDR2, DDRGK1 | CNR1 2761/4885CNR2 3824/4885PDE5A 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.