Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 7/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29873478 | 1.00 | CNR1 (0.43) | CNR1CNR2PDE5AACVR1BTGFBR1 | |
| SCHEMBL29872865 | 0.88 | PDE1B (0.50) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29872986 | 0.88 | CNR2 (0.45) | CNR1CNR2PDE5AACVR1BTGFBR1 | |
| SCHEMBL23069164 | 0.88 | PDE1B (0.50) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29872618 | 0.83 | CNR1 (0.39) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29872989 | 0.82 | BUB1 (0.40) | CNR1CNR2PDE5AMAPTALDH1A1 | |
| SCHEMBL29872928 | 0.80 | KDM4E (0.43) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29872787 | 0.80 | PDE1B (0.42) | CNR1CNR2PDE5ANPBWR1MAPT | |
| SCHEMBL29873129 | 0.80 | MAPT (0.46) | CNR1CNR2PDE5AMAPTLMNA | |
| SCHEMBL29873410 | 0.78 | PDE1B (0.43) | CNR1CNR2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4025570-A1 | HYDANTOIN DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2022-07-13 | — | — | EP | disclosed |
| WO-2021043245-A1 | HYDANTOIN DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-03-11 | — | — | WO | disclosed |