SCHEMBL230693

SCHEMBL230693

C=CC(=O)OCCCCO[SiH](C)C

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.67
ALDH1A1 P00352 4/20 0.67
CYP3A4 P08684 2/20 0.67
HPGD P15428 1/20 0.60
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 3/20 0.38
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NAAA Q02083 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26918628 0.98 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL537087 0.96 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1779326 0.88 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL244114 0.83 TSHR (0.95) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3389472 0.81 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9101988 0.81 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8493780 0.81 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL13945622 0.81 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20873747 0.81 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL33725 0.81 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed
US-20240158904-A1 UNDERCOAT AGENT COMPOSITION FOR LAYERING INORGANIC MATERIAL LAYER, CURED PRODUCT THEREOF AND PRODUCTION METHOD THEREOF TOAGOSEI CO., LTD. (JP) 2024-05-16 US disclosed
EP-4289618-A1 UNDERCOAT AGENT COMPOSITION FOR INORGANIC SUBSTANCE LAYER LAMINATION, CURED PRODUCT THEREOF, AND METHOD FOR PRODUCING SAME Toagosei Co., Ltd. (JP) 2023-12-13 EP disclosed
CN-111533854-B Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2023-03-31 CN disclosed
WO-2022168804-A1 UNDERCOAT AGENT COMPOSITION FOR INORGANIC SUBSTANCE LAYER LAMINATION, CURED PRODUCT THEREOF, AND METHOD FOR PRODUCING SAME 東亞合成株式会社 2022-08-11 WO disclosed
CN-113265053-A Catalyst having polysiloxane structural units for curable compositions SIKA技术股份公司 2021-08-17 CN disclosed
CN-108473815-B Catalyst having polysiloxane structural units for curable compositions SIKA技术股份公司 2021-05-28 CN disclosed
CN-109803826-B Laminate and method for producing same 信越化学工业株式会社 2021-05-11 CN disclosed
CN-108472685-B Method for producing laminate 信越化学工业株式会社 2021-02-02 CN disclosed
US-10836868-B2 Catalyst having a polysiloxane structural unit for hardenable compositions SIKA TECHNOLOGY AG (CH) 2020-11-17 US disclosed
EP-1170109-A1 Photocuring resin compositions, photocuring sheets and molded article using the same and processes of production thereof Mitsubishi Rayon Co., Ltd. (JP) 2002-01-09 EP disclosed
US-6136886-A RUBBER KABUSHIKI KAISHA SHOFU (JP) 2000-10-24 US disclosed
US-6063830-A SILICA AND URETHANEACRYLATE KABUSHIKI KAISHA SHOFU (JP) 2000-05-16 US disclosed
US-6028127-A Artificial marble and method for preparing it MITSUBISHI RAYON CO., LTD. (JP) 2000-02-22 US disclosed
EP-0786440-A1 ARTIFICIAL MARBLE AND PROCESS FOR PRODUCING THE SAME MITSUBISHI RAYON CO., LTD. (JP) 1997-07-30 EP disclosed
EP-0534753-B1 Composite composition having high transparency and process for producing same MITSUBISHI RAYON CO (JP) 1996-12-18 EP disclosed
US-5385988-A A curable blends consisting of an additional polymer and a polysilicates, polysiloxanes or polysilsesquioxanes in a dispersion system of colloidal silica to form rigid, tough interpenetrating polymer networks MITSUBISHI RAYON CO., LTD. (JP) 1995-01-31 US disclosed
EP-0534753-A1 Composite composition having high transparency and process for producing same MITSUBISHI RAYON CO., LTD. (JP) 1993-03-31 EP disclosed
US-5153091-A Development of magnetic latent images using toner containing encapsulated polylauryl methacrylate/magnetite core and polyurea shell blended with non-encapsulated polybutyl methacrylate-styrene copolymer/magnetite XEROX CORPORATION (US) 1992-10-06 US disclosed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US disclosed