SCHEMBL537087

SCHEMBL537087

C=CC(=O)OCCCO[SiH](C)C

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.61
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 2/20 0.61
HPGD P15428 1/20 0.60
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HCAR2 Q8TDS4 3/20 0.35
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230693 0.96 TSHR (0.67) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL26918628 0.94 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1779326 0.88 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL321925 0.83 TSHR (0.85) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL108948 0.81 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28470987 0.81 TSHR (0.81) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL244114 0.79 TSHR (0.95) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1585542 0.78 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3389472 0.78 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL439108 0.78 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833865-A1 CROSS-LINKABLE, SILANE-MODIFIED COPOLYMERS Consortium für elektrochemische Industrie GmbH (DE) 2007-09-19 EP claimed
WO-2006072411-A1 CROSS-LINKABLE, SILANE-MODIFIED COPOLYMERS WACKER CHEMIE AG (DE) 2006-07-13 WO claimed
CN-111533854-B Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2023-03-31 CN disclosed
CN-109803826-B Laminate and method for producing same 信越化学工业株式会社 2021-05-11 CN disclosed
CN-108472685-B Method for producing laminate 信越化学工业株式会社 2021-02-02 CN disclosed
EP-3045506-B1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE SHINETSU CHEMICAL CO (JP) 2020-03-04 EP disclosed
US-20190291394-A1 LAMINATED BODY AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-09-26 US disclosed
EP-3527366-A1 LAMINATED BODY AND PRODUCTION METHOD THEREFOR Shin-Etsu Chemical Co., Ltd. (JP) 2019-08-21 EP disclosed
US-10196409-B2 Organosilicon compound and curable composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-02-05 US disclosed
EP-3210988-B1 ORGANOSILICON COMPOUND AND CURABLE COMPOSITION SHINETSU CHEMICAL CO (JP) 2018-06-20 EP disclosed
EP-3210988-A1 ORGANOSILICON COMPOUND AND CURABLE COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2017-08-30 EP disclosed
US-20170240573-A1 ORGANOSILICON COMPOUND AND CURABLE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-24 US disclosed
US-20160208132-A1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-07-21 US disclosed
EP-3045506-A1 ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE Shin-Etsu Chemical Co., Ltd. (JP) 2016-07-20 EP disclosed
EP-2414466-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF Coatings GmbH (DE) 2012-02-08 EP disclosed
WO-2010112106-A1 MOISTURE-CURING COATING COMPOSITIONS BASED ON APROTIC SOLVENTS, COMPRISING BINDERS HAVING ALKOXYSILANE GROUPS, AND THE USE THEREOF BASF COATINGS AG (DE) 2010-10-07 WO disclosed
US-20070098653-A1 Non-aqueous liquid composition having ultraviolet-absorbing capability TAISEI FINE CHEMICAL CO., LTD. (JP) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10196409-B2 Organosilicon compound and curable composition MASTL, PIEZO1, MCM6 TSHR 3198/4885ALDH1A1 1875/4885CYP3A4 2654/4885
US-20070098653-A1 Non-aqueous liquid composition having ultraviolet-absorbing capability CUTA, CCNY, PCNA TSHR 1991/4885ALDH1A1 2672/4885CYP3A4 3441/4885
US-20170240573-A1 ORGANOSILICON COMPOUND AND CURABLE COMPOSITION MASTL, PIEZO1, MCM6 TSHR 3198/4885ALDH1A1 1875/4885CYP3A4 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.