Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.88 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.88 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.88 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.88 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.88 |
| ▸ | PKM | P14618 | 2/20 | 0.88 |
| ▸ | TYR | P14679 | 2/20 | 0.88 |
| ▸ | CA12 | O43570 | 2/20 | 0.88 |
| ▸ | CA4 | P22748 | 2/20 | 0.88 |
| ▸ | CA6 | P23280 | 2/20 | 0.88 |
| ▸ | CA5A | P35218 | 2/20 | 0.88 |
| ▸ | CA7 | P43166 | 2/20 | 0.88 |
| ▸ | CA9 | Q16790 | 2/20 | 0.88 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.88 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.88 |
| ▸ | CA1 | P00915 | 1/20 | 0.88 |
| ▸ | CA2 | P00918 | 1/20 | 0.88 |
| ▸ | CA3 | P07451 | 1/20 | 0.88 |
| ▸ | DPP4 | P27487 | 1/20 | 0.88 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumaric Acid SCHEMBL15014255 | 1.00 | ESR1 (0.88) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Cinnamic Acid SCHEMBL16982631 | 0.94 | ESR1 (0.83) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Cinnamic Acid SCHEMBL29095852 | 0.94 | HCAR2 (0.83) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Cinnamic Acid SCHEMBL16982629 | 0.94 | ESR1 (0.83) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Coumaric Acid SCHEMBL6333097 | 0.94 | ESR1 (1.00) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Coumaric Acid SCHEMBL20702657 | 0.94 | ESR1 (1.00) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Coumaric Acid SCHEMBL43601 | 0.94 | ESR1 (1.00) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Coumaric Acid SCHEMBL6333102 | 0.94 | ESR1 (1.00) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Coumaric Acid SCHEMBL434720 | 0.94 | ESR1 (1.00) | ESR1ESR2AKR1B10AKR1B1HCAR2 | |
| Coumaric Acid SCHEMBL39106 | 0.94 | ESR1 (1.00) | ESR1ESR2AKR1B10AKR1B1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046388-A1 | COMPOSITIONS AND METHODS FOR COGNITIVE PROTECTION OF POLLINATORS AGAINST PESTICIDES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-03-11 | — | — | WO | disclosed |