Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.83 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.83 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.83 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.83 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.83 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.83 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.83 |
| ▸ | TNKS | O95271 | 1/20 | 0.83 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.83 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.83 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.83 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.83 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.83 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.83 |
| ▸ | ESR1 | P03372 | 4/20 | 0.76 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.76 |
| ▸ | PKM | P14618 | 2/20 | 0.76 |
| ▸ | TYR | P14679 | 2/20 | 0.76 |
| ▸ | CA1 | P00915 | 2/20 | 0.76 |
| ▸ | CA2 | P00918 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Acid SCHEMBL16982629 | 0.96 | ESR1 (0.83) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL16982631 | 0.96 | ESR1 (0.83) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Coumaric Acid SCHEMBL23070211 | 0.94 | ESR1 (0.88) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Coumaric Acid SCHEMBL15014255 | 0.94 | ESR1 (0.88) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL3406486 | 0.91 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL653828 | 0.91 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL653827 | 0.91 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL1332 | 0.91 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL1706935 | 0.91 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL50466 | 0.91 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535366-B | Thiazole compound and preparation method and application thereof | 广州医科大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-116535366-B | Thiazole compound and preparation method and application thereof | 广州医科大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-116535366-A | Thiazole compound and preparation method and application thereof | 广州医科大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-116535366-A | Thiazole compound and preparation method and application thereof | 广州医科大学 | 2023-08-04 | — | — | CN | disclosed |