Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068094 | 0.85 | CHRM2 (0.33) | BRD4ALDH1A1 | |
| SCHEMBL208987 | 0.83 | PRKCA (0.35) | BRD4ALDH1A1 | |
| SCHEMBL2633146 | 0.83 | BRD4 (0.31) | BRD4 | |
| SCHEMBL2633145 | 0.82 | LMNA (0.31) | — | |
| SCHEMBL4786241 | 0.81 | APEX1 (0.31) | — | |
| SCHEMBL17194184 | 0.81 | BRD4 (0.33) | BRD4 | |
| SCHEMBL18538124 | 0.81 | BRD4 (0.33) | BRD4 | |
| SCHEMBL12457814 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1 | |
| SCHEMBL29293697 | 0.80 | PRKCA (0.38) | — | |
| SCHEMBL10066994 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941139-B2 | Cryptophycin compounds and conjugates, their preparation and their therapeutic use | SANOFI (FR) | 2021-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941139-B2 | Cryptophycin compounds and conjugates, their preparation and their therapeutic use | XPOT, COIL, HCCS | BRD4 4409/4885TRPA1 4841/4885ALDH1A1 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.