Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050417 | 0.82 | RIPK1 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4GBA1 | |
| SCHEMBL525671 | 0.82 | RIPK1 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4GBA1 | |
| SCHEMBL6050532 | 0.82 | RIPK1 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4GBA1 | |
| SCHEMBL29457634 | 0.78 | GBA1 (0.45) | GBA1HTR1AALOX5GPR88CTSS | |
| SCHEMBL29967173 | 0.78 | GBA1 (0.45) | GBA1HTR1AALOX5GPR88CTSS | |
| SCHEMBL20309012 | 0.78 | GBA1 (0.45) | GBA1HTR1AALOX5GPR88CTSS | |
| SCHEMBL18551012 | 0.77 | HIF1A (0.43) | HTR1AGPR88PDK2RIPK1 | |
| SCHEMBL9244730 | 0.77 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4HTR1A | |
| SCHEMBL3461 | 0.77 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4HTR1A | |
| SCHEMBL6050462 | 0.76 | MEN1 (0.40) | GPR88PDK2RIPK1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941138-B2 | Quinoline and isoquinoline derivatives for treating pain and pain related conditions | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941138-B2 | Quinoline and isoquinoline derivatives for treating pain and pain related conditions | CACNA1B, SCN2A, CACNA1C | CHRNB2 57/4885CHRNB4 102/4885CHRNA3 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.