Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152713 | 0.87 | BRD4 (0.46) | BRD4BRD9PKMPKLR | |
| SCHEMBL23473027 | 0.85 | BRD4 (0.46) | BRD4GRIN1GRIN2BKMT2AKDM4E | |
| SCHEMBL18152880 | 0.84 | BRD4 (0.45) | BRD4GRIN1GRIN2BKMT2AMAPT | |
| SCHEMBL23073030 | 0.77 | BRD4 (0.44) | BRD4GRIN1GRIN2BP2RX7 | |
| SCHEMBL18164205 | 0.76 | BRD4 (0.43) | BRD4GRIN1GRIN2BKMT2AMAPT | |
| SCHEMBL23073072 | 0.73 | BRD4 (0.49) | BRD4BRD9 | |
| SCHEMBL18164309 | 0.73 | BRD4 (0.44) | BRD4KMT2ABRD9PKMPKLR | |
| SCHEMBL18538434 | 0.72 | BRD4 (0.46) | BRD4GRIN1GRIN2BBRD9 | |
| SCHEMBL18152720 | 0.72 | BRD4 (0.47) | BRD4 | |
| SCHEMBL18152634 | 0.71 | BRD4 (0.54) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-B1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2021-03-10 | — | — | EP | disclosed |