SCHEMBL230733

SCHEMBL230733

COC(c1ccccc1)C(OC)(OC)O[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33
EPHX1 P07099 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230734 0.80 KMT2A (0.35) KMT2AEPHX1THRB
SCHEMBL4244344 0.78 KMT2A (0.36) KMT2AEPHX1THRB
SCHEMBL19356700 0.76 MAPK1 (0.33) KMT2AEPHX1THRB
SCHEMBL14663964 0.73 ATM (0.40) KMT2AEPHX1THRB
SCHEMBL12344306 0.73 ATM (0.40) KMT2AEPHX1THRB
SCHEMBL11911981 0.73 ATM (0.40) KMT2AEPHX1THRB
SCHEMBL10512562 0.72 KMT2A (0.39) KMT2AEPHX1THRB
SCHEMBL30261324 0.72 DPP4 (0.36) KMT2AEPHX1THRB
SCHEMBL30296865 0.72 KMT2A (0.35) KMT2AEPHX1THRB
SCHEMBL7715366 0.71 NPSR1 (0.43) KMT2AEPHX1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10702467-B2 Emulsion containing organosilicon-based portions of hollow spheres L'ORÉAL (FR) 2020-07-07 US claimed
US-20170304183-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'ORÉAL (FR) 2017-10-26 US claimed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US claimed
US-20130224267-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2013-08-29 US claimed
US-20110217346-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2011-09-08 US claimed
EP-1530961-B1 Emulsion containing hollow organosilicon particles OREAL (FR) 2009-08-05 EP claimed
US-20050118218-A1 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2005-06-02 US claimed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP claimed
US-10702467-B2 Emulsion containing organosilicon-based portions of hollow spheres L'ORÉAL (FR) 2020-07-07 US disclosed
EP-3021948-B1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS OREAL (FR) 2019-08-21 EP disclosed
US-20170304183-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'ORÉAL (FR) 2017-10-26 US disclosed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US disclosed
EP-2462197-B1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF ORÉAL L (FR) 2016-09-21 EP disclosed
WO-2016116475-A1 O/O EMULSION CONTAINING MICROPARTICLES WITH A BREAK IN THE CURVATURED PART, COMPOSITIONS COMPRISING SAME AND USE OF MICROPARTICLES FOR STABILIZING THE O/O EMULSIONS L'OREAL (FR) 2016-07-28 WO disclosed
EP-1579841-A1 Cosmetic composition comprising concave particles L'OREAL (FR) 2005-09-28 EP disclosed
EP-1579849-A1 Cosmetic compositions comprising concave particles. L'OREAL (FR) 2005-09-28 EP disclosed
US-20050118218-A1 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2005-06-02 US disclosed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP disclosed
US-4840983-A CABLE INSULATION; POLYOLEFINS AND ORGANOSILANE COMPOUNDS DOW CORNING CORPORATION (US) 1989-06-20 US disclosed
EP-0247392-A2 Anti treeing additives DOW CORNING CORPORATION (US) 1987-12-02 EP disclosed