SCHEMBL230734

SCHEMBL230734

COC(OC)(OC)C(O[SiH3])c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
DPP4 P27487 2/20 0.31
F2 P00734 1/20 0.31
TSHR P16473 1/20 0.31
CA4 P22748 1/20 0.31
EPHX1 P07099 1/20 0.31
THRB P10828 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ACP3 P15309 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31
RIPK1 Q13546 1/20 0.31
HTR2A P28223 1/20 0.30
HRH1 P35367 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225533 0.80 POLB (0.40) KMT2ATSHRALDH1A1
SCHEMBL230733 0.80 KMT2A (0.33) KMT2AEPHX1THRB
SCHEMBL705886 0.78 ATM (0.39) KMT2ADPP4RIPK1HRH1
SCHEMBL10713851 0.74 TSHR (0.39) DPP4F2TSHRALDH1A1IDO1
SCHEMBL5570358 0.73 LMNA (0.38) RIPK1HTR2AHRH1
SCHEMBL29157994 0.72 MAPK1 (0.33) DPP4F2TSHRALDH1A1IDO1
SCHEMBL4244344 0.72 KMT2A (0.36) KMT2ADPP4F2TSHRCA4
SCHEMBL29002750 0.68 POLB (0.30)
SCHEMBL18297941 0.67 THRB (0.41) KMT2ADPP4F2TSHRCA4
SCHEMBL14663964 0.67 ATM (0.40) KMT2AEPHX1THRBRIPK1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10702467-B2 Emulsion containing organosilicon-based portions of hollow spheres L'ORÉAL (FR) 2020-07-07 US claimed
US-20170304183-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'ORÉAL (FR) 2017-10-26 US claimed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US claimed
US-20130224267-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2013-08-29 US claimed
US-20110217346-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2011-09-08 US claimed
EP-1530961-B1 Emulsion containing hollow organosilicon particles OREAL (FR) 2009-08-05 EP claimed
US-20050118218-A1 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2005-06-02 US claimed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP claimed
EP-3021948-B1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS OREAL (FR) 2019-08-21 EP disclosed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US disclosed
EP-2462197-B1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF ORÉAL L (FR) 2016-09-21 EP disclosed
WO-2016116475-A1 O/O EMULSION CONTAINING MICROPARTICLES WITH A BREAK IN THE CURVATURED PART, COMPOSITIONS COMPRISING SAME AND USE OF MICROPARTICLES FOR STABILIZING THE O/O EMULSIONS L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116492-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST A FIRST OILY PHASE, AT LEAST A SECOND OILY PHASE AND AT LEAST A THIRD OILY PHASE THAT ARE MUTUALLY IMMISCIBLE L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116488-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST ONE HYDROCARBON-BASED RESIN, AT LEAST A FIRST OILY PHASE AND AT LEAST A SECOND OILY PHASE L'OREAL (FR) 2016-07-28 WO disclosed
EP-1579841-A1 Cosmetic composition comprising concave particles L'OREAL (FR) 2005-09-28 EP disclosed
EP-1579849-A1 Cosmetic compositions comprising concave particles. L'OREAL (FR) 2005-09-28 EP disclosed
US-20050118218-A1 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2005-06-02 US disclosed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP disclosed
US-4840983-A CABLE INSULATION; POLYOLEFINS AND ORGANOSILANE COMPOUNDS DOW CORNING CORPORATION (US) 1989-06-20 US disclosed
EP-0247392-A2 Anti treeing additives DOW CORNING CORPORATION (US) 1987-12-02 EP disclosed