Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23073332 | 0.83 | PARP1 (0.60) | PARP1 | |
| SCHEMBL23064718 | 0.81 | PARP1 (0.69) | PARP1 | |
| SCHEMBL14233393 | 0.80 | PARP1 (0.80) | PARP1 | |
| SCHEMBL15917987 | 0.80 | PARP1 (0.68) | PARP1 | |
| SCHEMBL15917988 | 0.80 | PARP1 (0.67) | PARP1 | |
| SCHEMBL24113949 | 0.78 | PARP1 (0.45) | PARP1 | |
| SCHEMBL23073370 | 0.77 | PARP1 (0.53) | PARP1 | |
| SCHEMBL12955373 | 0.74 | LMNA (0.68) | PARP1 | |
| SCHEMBL15917661 | 0.73 | PARP1 (0.83) | PARP1 | |
| SCHEMBL15918645 | 0.73 | PARP1 (0.83) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714703-B1 | TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | NEWGEN THERAPEUTICS INC (US) | 2021-03-10 | — | — | EP | disclosed |