Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23074674 | 0.84 | HRH3 (0.47) | KCNH2MEN1KMT2AHRH3NFE2L2 | |
| SCHEMBL15759205 | 0.84 | KDM4E (0.51) | KDM4EKCNH2MEN1KMT2AHRH3 | |
| SCHEMBL23074708 | 0.84 | F2 (0.41) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL23074697 | 0.84 | HTR2A (0.47) | KDM4EMEN1KMT2AHRH3NFE2L2 | |
| SCHEMBL23074671 | 0.83 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL23074677 | 0.83 | HRH3 (0.50) | KDM4EMEN1KMT2AHRH3NFE2L2 | |
| SCHEMBL23074692 | 0.83 | KMT2A (0.48) | KDM4EMEN1KMT2AHRH3NFE2L2 | |
| SCHEMBL23074711 | 0.82 | MEN1 (0.52) | KDM4EMEN1KMT2ADRD2DRD4 | |
| SCHEMBL23074699 | 0.81 | ALDH1A1 (0.43) | NFE2L2ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23074701 | 0.81 | ALDH1A1 (0.43) | NFE2L2ALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210069692-A1 | ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS | BIO-RAD LABORATORIES, INC. | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210069692-A1 | ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS | ABCG2, SLC7A1, MSR1 | KDM4E 3830/4885KCNH2 1383/4885MEN1 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.