Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10264447 | 0.85 | LTA4H (0.45) | HRH3ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL23074644 | 0.84 | KDM4E (0.51) | HRH3ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23074697 | 0.81 | HTR2A (0.47) | HRH3ALDH1A1LMNASMN1; SMN2LTA4H | |
| SCHEMBL23074671 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL23074677 | 0.81 | HRH3 (0.50) | HRH3ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL23074692 | 0.81 | KMT2A (0.48) | HRH3ALDH1A1LMNASMN1; SMN2LTA4H | |
| SCHEMBL2352010 | 0.79 | HTR2A (0.52) | HRH3ALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL2352960 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LTA4HCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2351409 | 0.78 | HTR2A (0.51) | HRH3ALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL23074701 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LTA4HCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210069692-A1 | ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS | BIO-RAD LABORATORIES, INC. | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210069692-A1 | ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS | ABCG2, SLC7A1, MSR1 | HRH3 10/4885ALDH1A1 4738/4885LMNA 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.