Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23085752 | 0.91 | RIPK1 (0.59) | RIPK1 | |
| SCHEMBL25077587 | 0.89 | RIPK1 (0.60) | RIPK1 | |
| SCHEMBL23075456 | 0.89 | RIPK1 (0.61) | RIPK1 | |
| SCHEMBL26381841 | 0.85 | RIPK1 (0.56) | RIPK1 | |
| SCHEMBL21531284 | 0.85 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL21531281 | 0.85 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL21531314 | 0.84 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL21531311 | 0.84 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL30635182 | 0.81 | RIPK1 (0.82) | RIPK1 | |
| SCHEMBL24076710 | 0.81 | RIPK1 (0.64) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046447-A1 | HETEROCYCLIC RIP1 KINASE INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |