Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23075319 | 0.91 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL23075456 | 0.88 | RIPK1 (0.61) | RIPK1 | |
| SCHEMBL22968458 | 0.84 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL25077587 | 0.82 | RIPK1 (0.60) | RIPK1 | |
| SCHEMBL25586520 | 0.80 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL23085493 | 0.80 | RIPK1 (0.65) | RIPK1 | |
| SCHEMBL23075318 | 0.80 | RIPK1 (0.64) | RIPK1 | |
| SCHEMBL23085729 | 0.78 | RIPK1 (0.62) | RIPK1 | |
| SCHEMBL23075315 | 0.77 | RIPK1 (0.54) | RIPK1 | |
| SCHEMBL23085733 | 0.77 | RIPK1 (0.63) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046407-A1 | RIP1 INHIBITORY COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |