Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988636 | 0.83 | GSK3B (0.73) | GSK3BF2DAOALDH1A1HPGD | |
| SCHEMBL1985851 | 0.81 | GSK3B (0.70) | GSK3BF2DAOALDH1A1HPGD | |
| SCHEMBL3999321 | 0.81 | GSK3B (1.00) | GSK3BF2DAOALDH1A1HPGD | |
| SCHEMBL11172498 | 0.79 | GSK3B (0.62) | GSK3BF2DAO | |
| SCHEMBL17459466 | 0.79 | GSK3B (0.68) | GSK3BF2DAOALDH1A1HPGD | |
| SCHEMBL1359642 | 0.78 | GSK3B (0.67) | GSK3BALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL11607360 | 0.78 | GSK3B (0.56) | GSK3BDAOALDH1A1HPGDPOLB | |
| SCHEMBL982447 | 0.78 | GSK3B (0.71) | GSK3BF2DAOALDH1A1HPGD | |
| SCHEMBL27579199 | 0.78 | GSK3B (0.66) | GSK3BF2DAOALDH1A1HPGD | |
| SCHEMBL193501 | 0.77 | GSK3B (1.00) | GSK3BDAOALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001089447-A2 | ANTIFUNGAL SUBSTITUTED PROPYL TRIAZOLE COMPOUND, ITS SALT, AND PREPARATION METHODS THEREOF | SECOND MILITARY MEDICAL UNIVERSITY OF PLA. (CN) | 2001-11-29 | — | — | WO | claimed |
| CN-112839942-B | 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2024-08-23 | — | — | CN | disclosed |
| US-11958844-B2 | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-04-16 | — | — | US | disclosed |
| EP-3827004-B1 | 4-(1,3,4-OXADIAZOLE-2-YL)PYRIDINE-2(1H)-ONE DERIVATIVES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS FOR THE TREATMENT OF E.G. INFECTIONS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-10-11 | — | — | EP | disclosed |
| EP-3827004-B1 | 4-(1,3,4-OXADIAZOLE-2-YL)PYRIDINE-2(1H)-ONE DERIVATIVES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS FOR THE TREATMENT OF E.G. INFECTIONS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-10-11 | — | — | EP | disclosed |
| US-20230257395-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-08-17 | — | — | US | disclosed |
| US-20230257395-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-08-17 | — | — | US | disclosed |
| US-11661430-B2 | Tetrazole derivatives as TRPA1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-05-30 | — | — | US | disclosed |
| US-11661427-B2 | Tetrazole derivatives as TRPA1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-05-30 | — | — | US | disclosed |
| US-11661427-B2 | Tetrazole derivatives as TRPA1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-05-30 | — | — | US | disclosed |
| EP-0641794-A1 | Thienyl- and furylpyrrole derivatives, their preparation and their use as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0436736-B1 | THERMAL TRANSFER SHEET | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5187145-A | Imidazole dye derivatives | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0436736-A1 | THERMAL TRANSFER SHEET | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4492695-A | ANTICONVULSANTS, SEDATIVES, TRANQUILIZERS | SYNTHELABO (FR) | 1985-01-08 | — | — | US | disclosed |
| EP-0097480-A1 | Triazole antifungal agents | Pfizer Limited (GB) | 1984-01-04 | — | — | EP | disclosed |
| US-4105663-A | HYPOTENSIVE, BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
| US-4093628-A | HYPOTENSIVE AGENTS, BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4017631-A | MICROBIOCIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-04-12 | — | — | US | disclosed |
| US-3991202-A | ANTIMICROBIALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257395-A1 | TETRAZOLE DERIVATIVES AS TRPA1 INHIBITORS | TRPA1, TRPV1, TRPV5 | GSK3B 3802/4885F2 4735/4885DAO 1811/4885 |
| US-11958844-B2 | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same | HDAC6, HDAC1, HDAC3 | GSK3B 180/4885F2 4806/4885DAO 2675/4885 |
| US-11661427-B2 | Tetrazole derivatives as TRPA1 inhibitors | TRPA1, TRPV1, TRPV5 | GSK3B 3864/4885F2 4744/4885DAO 1673/4885 |
| US-11661430-B2 | Tetrazole derivatives as TRPA1 inhibitors | TRPA1, TRPV1, TRPV5 | GSK3B 3864/4885F2 4744/4885DAO 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.