Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23078761 | 0.88 | CD274 (0.50) | CD274PDCD1MRGPRX4 | |
| SCHEMBL23078654 | 0.86 | PDCD1 (0.43) | CD274PDCD1MRGPRX4 | |
| SCHEMBL23078807 | 0.86 | PDCD1 (0.42) | ERN1CD274PDCD1MRGPRX4 | |
| SCHEMBL23078657 | 0.84 | PDCD1 (0.44) | CD274PDCD1MRGPRX4 | |
| SCHEMBL22757792 | 0.82 | CD274 (0.52) | ERN1CD274PDCD1TDP1 | |
| SCHEMBL23078496 | 0.80 | CD274 (0.48) | CD274PDCD1MRGPRX4 | |
| SCHEMBL23078779 | 0.80 | PDCD1 (0.51) | CD274PDCD1 | |
| SCHEMBL18728442 | 0.79 | CD274 (0.51) | ERN1CD274PDCD1 | |
| SCHEMBL28999576 | 0.79 | MRGPRX4 (0.42) | CD274PDCD1MRGPRX4MAPT | |
| SCHEMBL23078432 | 0.79 | MRGPRX4 (0.45) | CD274PDCD1MRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043116-A1 | BIPHENYL COMPOUNDS, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国药科大学 | 2021-03-11 | — | — | WO | disclosed |